's-Hertogenbosch (Dutch pronunciation: [ˌsɛrtoːɣə(m)ˈbɔs] ⓘ) is a railway station located in 's-Hertogenbosch in North Brabant, Netherlands.

's-Hertogenbosch station opened on 1 November 1868 as the northern terminus of the southern part of the Utrecht–Boxtel railway (Staatslijn H), with service south to Boxtel.

As the town was a fortress at the time, the station was designed with attack in mind; its wood truss construction allowed it to be dismantled or damaged with minimal waste.

During World War II, at 16 September 1944, the station caught fire and burnt down; it was never rebuilt to its former glory.

Much of the renovation consisted of an aerial walkway, the Stationspasserelle, connecting the roadways on either side of the tracks, and the removal of a special ramp to the platforms.