[2] He then played almost his entire career with Deportivo Saprissa, winning three league titles and holding the club record for most goals scored until it was broken in the 1970s by Edgar Marín.
Murillo was part of the Saprissa team that went on a World Tour in 1959, becoming the first Latin American football squad to ever undertake such a trip.
He was also the Tour's top goal scorer, which led to offers from European clubs such as Genoa of Italy, Huracán of Argentina and Austria Wien, as well as teams from Venezuela and Mexico.
With Costa Rica's national team, Murillo was part of the Chaparritos de Oro squad that won a silver medal in the Pan-American Games held in Buenos Aires during the 1950s.
[3] He earned a total of 36 caps, scoring 9 goals[2][4] and represented his country in 6 FIFA World Cup qualification matches.