Circa 2003, he became Deputy Chairman of the State Service of Turkmenistan for the Registration of Foreign Citizens and from early- to mid-2007 was in the same position again.

From April 2018 to 2020, he served in the post of rector of the Institute of the Ministry of Internal Affairs of Turkmenistan, holding the rank of major general of police.

[4][5] Eight days later, he was appointed by President Gurbanguly Berdimuhamedow to the post of Deputy Chairman of the Cabinet of Ministers responsible for Security, Military, and Justice (a de facto deputy prime minister) and concurrently Secretary of the State Security Council.

[12] The following week, on 4 October 2021, the president issued Amanow a "stern reprimand with final warning" for weak control of subordinates.

[13] His position as deputy chairman of the Cabinet of Ministers for security, military, and justice was abolished by presidential decree on 6 April 2022, and Amanow was transferred "to other work".