The song is certified Platinum or higher in twelve countries, including Diamond in Brazil, France, Poland, and Mexico.

[4] On November 1, 2017, MTV News reported that the collaboration would be titled "Échame la Culpa", a song Fonsi has been performing solo during live shows across the summer.

[6] In a clip shared by Billboard on November 13, 2017, Lovato and Fonsi can be seen meeting each other via a FaceTime call to discuss details about their collaboration.

[19] Ross McNeilage of the same publication deemed the song "an absolute powerhouse anthem that goes harder than 'Despacito' ever did", and gave credit to "Demi's flawless Spanish and [Fonsi and Lovato's] undeniable chemistry".

[21] The music video first takes place in Lovato's bedroom, before the duo meet up in an abandoned warehouse and hold a dance party.

[25] As of June 2020, "Échame la Culpa" has reached 2 billion views, making it one of the site's 60 most-viewed videos.

Fonsi later performed the song at the 2019 Pan American Games in Perú alongside Peruvian singer Leslie Shaw.