Her elder brother, Michel Scob (1935–1995), was a French cycling champion and Olympian.

[3] Scob was studying French at the Sorbonne and taking drama classes when she was cast in her first role.

[5] Scob made her debut in theater in 1958 with the play Don Juan directed by Georges Vitaly but she gained a high profile early in her career when she appeared in Eyes Without a Face (1960).

She was twice nominated for the César Award for Best Supporting Actress for Summer Hours (2008)[6] and Holy Motors (2012).

[1][7] Following the events of May 1968, Scob founded an avant-garde theatre in Bagnolet with her husband, composer Georges Aperghis, with the goal of introducing more culture to the most disadvantaged people.