Édouard Séguin (January 20, 1812 – October 28, 1880) was a French physician and educationist born in Clamecy, Nièvre.

As a young man, Séguin was also influenced by the ideas of utopian socialist Henri de Saint-Simon.

After visiting various schools, modeled on his own, that had been established in the United States, and assisting in their organization, he settled in Cleveland, and later in Portsmouth, Ohio.

In 1863 he moved to New York City, where he made efforts to improve conditions of children with disabilities at Randall's Island asylum.

In addition, a medical symptom known as "Séguin's signal" is named after him, being described as an involuntary muscle contraction prior to an epileptic attack.