Bussaglia is a former winner of the National Union of Professional Footballers (UNFP) Female Player of the Year having won the award after a successful 2010–11 season with Paris Saint-Germain.
After leaving the academy, she joined D1 Féminine club FCF Juvisy playing 14 matches and scoring two goals in her first season.
At Montpellier, Bussaglia became an established international player and helped Montpellier to two top table finishes, including helping the team win the 2008–09 Challenge de France and qualify for the newly created UEFA Women's Champions League in her final season.
In 2009, Bussaglia signed with Paris Saint-Germain and, in the process, joined a club which included international teammates Camille Abily, Sonia Bompastor, Bérangère Sapowicz, and Laure Boulleau.
The midfielder compensated her uneventful performance in the league with a decent showing in the Challenge de France netting the fourth goal in Paris Saint-Germain's 5–0 win over her former club Montpellier in the competition's final match.