[3] Later that year, he co-chaired (with Marie Guévenoux) a group of some twenty parliamentarians involved in organizing a nation-wide consultation process in response to the Yellow vests movement.

[6] In May 2018, Bothorel co-sponsored an initiative in favour of a bioethics law extending to homosexual and single women free access to fertility treatments such as in vitro fertilisation (IVF) under France's national health insurance; it was one of the campaign promises of President Emmanuel Macron and marked the first major social reform of his five-year term.

[7][8] Along with four other LREM members – Cécile Rilhac, Jean-Michel Mis, Stéphane Trompille, and Coralie Dubost –, Bothorel disassociated himself from their colleague Aurore Bergé when the latter announced her intention in October 2019 to vote for a Republican draft law banning the wearing of the hijab by women accompanying groups of students on school outings.

[9] Amid efforts to contain the COVID-19 pandemic in France, Bothorel was one of the early supporters of the government's proposal for a state-supported “StopCovid” contact-tracing app project.

[10] In 2020, Bothorel was one of ten LREM members who voted against his parliamentary group's majority and opposed a much discussed security bill drafted by his colleagues Alice Thourot and Jean-Michel Fauvergue that helps, among other measures, curtail the filming of police forces.