[7] He had only a limited influence at Court, because of his initial sympathy for the Revolt of the Comuneros, for which he was imprisoned by his father.
[citation needed] He was a cultured man, who expanded significantly the library started by his ancestor Íñigo López de Mendoza, 1st Marquis of Santillana.
[citation needed] On 10 October 1513, the eventual 4th Duke married Isabel de Aragón y Portugal.
Her father was Enrique de Aragón y Pimentel, 1st Duke of Segorbe[3][11] (Calatayud, 1445 – Castelló d'Empúries, 1522),[12] also known as "Infante Fortuna".
[citation needed] The 7th Duke's mother Luisa was a daughter of the 6th Duchess's first marriage, with another Mendoza—Rodrigo de Mendoza—from this complicated family.
(This was distinct from the present-day Spanish naming customs under which a person takes two surnames, the first from his or her father and the second from his or her mother.)