Biscet was given a 25-year prison sentence in Cuba for allegedly committing crimes against the sovereignty and the integrity of the Cuban territory.

Henry David Thoreau, Mohandas Gandhi, and Martin Luther King Jr. are major influences in Biscet's writing and motivation.

[citation needed] The physician's wife, Elsa Morejón was also expelled from nursing (her profession) when her husband started to oppose a widespread use of Rivanol for abortions.

[5] In August 1999, Biscet, along with two dozen other dissidents, were detained by Cuban police for organizing meetings in Havana and Matanzas.

[7] One month after being released from custody,[6] on December 6, 2002, Biscet was arrested in a private house with 11 other dissidents while discussing a petition drive and human rights.

Biscet was one of the 75 dissidents imprisoned in 2003 by the Cuban authorities for his association with the head of the US Interests Section in Havana, James Cason.

He was subsequently held at Combinado del Este Prison in Havana, where he was generally not allowed outside visitors, including medical practitioners and clergy, under conditions described as "wretched".

[citation needed] Freedom Now, a non-profit organization located in Washington, D.C., was retained in 2005 to assist in obtaining Biscet's release from prison.

[citation needed] Nat Hentoff was one of the chief advocates for Biscet in the United States, penning numerous pleas in his syndicated and Village Voice column calling for his release, and highlighting his plight within the Cuban criminal justice system.