Örbyhus is a locality situated in Tierp Municipality, Uppsala County, Sweden with 2,153 inhabitants in 2018.

[3] Örbyhus Castle, located a few kilometers from the village, is where king Eric XIV of Sweden was imprisoned until his death from arsenic poisoning on 26 February 1577.

Libbarbo was a farm property located south of what is now Örbyhus, dating back to the 13th century.

In 1874, a railway station on the new railroad which connected Stockholm with Gävle was built, and formed the nucleus of the new village Örbyhus.

Bröderna Larssons Snickeri- & Skidfabrik, a ski manufacturer which also made garden furniture, kick sleds and toboggans, was built in 1905, and Örbyhus also had two textile factories in the first half of the 20th century.