Úpohlavy is a municipality and village in Litoměřice District in the Ústí nad Labem Region of the Czech Republic.

It has about 300 inhabitants.

Úpohlavy lies approximately 11 kilometres (7 mi) south-west of Litoměřice, 23 km (14 mi) south of Ústí nad Labem, and 50 km (31 mi) north-west of Prague.

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