She gained international recognition for her role as Tokyo in the crime drama series Money Heist (2017–2021) and made her Hollywood debut in the superhero film Snake Eyes (2021).

After leaving Física o Química, in 2011, Corberó landed a main role in Televisión Española's drama series 14 de abril.

[11] In 2012, she shot the television movie Los días de gloria which was also postponed due to political conflicts and broadcast in July 2013.

At the end of the year, she flew to Colombia to shoot Crimen con vista al Mar with Carmelo Gómez.

Men's Health's magazine named her Woman of the Year, an award that she received from the hand of her friend and legendary actress, Rossy de Palma.

[16][17] In 2015, Corberó went to Trento to shoot La Dama Velata, a Spanish-Italian coproduction starring Miriam Leone, Andrea Bosca and Aura Garrido.

[18] In March 2015, she starred as Nadia in Perdiendo el Norte alongside the actors Blanca Suarez and Yon Gonzalez.

[21] In 2015, she also landed her first main role in a movie in Cómo sobrevivir a una despedida and confirmed she's one of the best comical actresses of Spain.

In 2020, she starred in the music video of Un Día (One Day), a song by J Balvin, Dua Lipa, Bad Bunny and Tainy.

[30] The film, directed by Robert Schwentke and starring actors Henry Golding, Andrew Koji and Samara Weaving, was released on 23 July 2021 in Dolby Cinema and IMAX.

[31] In April 2022, Corberó joined the cast of Netflix's action film entitled Lift, starring Gugu Mbatha-Raw, Kevin Hart, Vincent D'Onofrio and Paul Anderson, among others.

[32] In September 2022, Corberó was announced as the lead of Netflix's new miniseries, based on a real story, entitled Burning Body (El cuerpo en llamas).

In February 2024, the actress joined Eddie Redmayne and Lashana Lynch in Sky and Peacock's new series The Day of the Jackal.

[44] Corberó is considered a "fashion icon" and created buzz with her Teresa Helbig dress, which featured a lateral opening that showed her leg, at the 30th Goya Awards.

[53] Corberó has participated in several breast cancer awareness campaigns with actresses Blanca Suarez and Clara Lago.

[54][55] Corberó also uses her platform to raise awareness about climate change and was a jury member of the 4th edition of the We Art Water Film Festival.

[56][53] In 2020, she participated to #REInventaElSistema, a campaign launched by Greenpeace to raise awareness about climate change following the COVID-19 pandemic, alongside personalities like anthropologist Jane Goodall, singer Alejandro Sanz, and actress Elena Anaya.

Corberó dated actor Israel Rodríguez from 2009 to 2011,[59] tennis player Feliciano López for five months in 2011,[60] and model Andrés Velencoso from 2013 to 2016.