In 1956, the National Assembly of the First Republic of Vietnam issued a decree to establish An Xuyên province in the area of Cà Mâu peninsula[note 3].

When the Vietnam War exploded, Việt Cộng partisans took advantage of the complex terrain of the district to fight the local government.

With its characteristics of the mangroves, Đầm Dơi population is concentrated mainly in the Northwest part of the rural district, where it has been exploited very early and has a complete inter-provincial road system.

The East of the district has a small river called Đầm Chim (means "swamp of birds"), which goes to the sea through Hố Gùi estuary.

Therefore, the project of the East-West Axis has been designed in 2024 with a system of roads and bridges to turn Đầm Dơi township into a transition point between two cities Bạc Liêu and Cà Mau.

The territory of the district has only one parish area called Bàu Sen, which located at Nam Chánh hamlet of Thanh Tùng commune, with about 50 parishioners.

Contrary to the poorness of the land fund for settlement, Đầm Dơi rural district was known early as one of the localities with the most prosperous customs in the Mekong Delta.

According to the traditional concept of the Southern Vietnamese, the Hoa (Tanka group) are said to be the first residents to reclaim the area of Đầm Dơi, then to the Kinh and Khmer.

According to local legends, there were two men, Tô Minh Chánh (Tanka) and Nguyễn Văn Lành (Kinh), from the Centre region to Đầm Dơi to reclaim and establish a village in 1820.

They decided to stay here to make a career, and at the same time, set up a temple to worship the goddess protecting the land (bà chúa xứ).

Gành Hào (means "canal of oysters") is a big seaport where was shared between the two districts Đầm Dơi and Đông Hải.

Đầm Dơi rural district has a 22km long coastline, which overlooks the East Sea, so it is very convenient for the development of the professions related to the maritime industry.

The future market is given priority located in the 2,533 square meters at the junction of the river[note 10], where is the center of Đầm Dơi township.