In 1407, the town already had its own wax seal with the coat of arms depicting the right, open and severed hand with the inscription "Łabiszyn".

Łabiszyn was a private town, administratively located in the Kcynia County in the Kalisz Voivodeship in the Greater Poland Province.

With the annexation of the town by Prussia in the late 18th-century Partitions of Poland, Protestant clothiers from German states began to arrive.

Another battle between Polish insurgents and the Prussian army near Łabiszyn took place in 1848, during the Greater Poland uprising, as part of the Revolutions of 1848.

After the German-Soviet invasion of Poland, which started World War II in September 1939, the town was invaded and occupied by Nazi Germany.