Łutselkʼe (/ˈlʊtsəlkeɪ/, Dëne Sųłıné Yatıé: [ɬutsʰɛɮk'ɛ]; "place of the łutsel", the cisco,[6] a type of small fish), also spelt Łutsël Kʼé, is a "designated authority"[7] in the North Slave Region of the Northwest Territories, Canada.

[8] Łutselkʼe is a First Nation community and the area was traditionally occupied by the Chipewyan Dene In 1925 the Hudson's Bay Company opened a post followed by the Roman Catholic Church.

[9] There is a proposal ongoing for Thaidene Nene National Park Reserve, with an area of 14,000 km2 (5,400 sq mi), which has the support of the community.

[21] There is a two-person Royal Canadian Mounted Police detachment and health centre with two nurses in the community.

Łutsel Kʼe is represented by the Łutsël K'é Dene First Nation and are part of the Akaitcho Territory Government.