It is named after the Ōme Kaidō highway which passes nearby the train station.
The station has a single side platform on a north-south axis, serving one ground-level bi-directional track.
[1] In fiscal 2019, the station was the 71st busiest on the Seibu network with an average of 8,367 passengers daily.
Ōmekaidō Station is a short walk from Shin-Kodaira on the JR Musashino Line.
This connection is sometimes recommended by JR reservations service and online route planners.