After both the Asakura and the Ikkō-ikki were destroyed by Oda Nobunaga in 1575, he assigned the area to his general Kanamori Nagachika under the regional control of Shibata Katsuie.

Kanamori was subsequently promoted to governor of Hida Province in 1586, and the area was assigned to Aoki Kazunori followed by Oda Hidekatsu by Toyotomi Hideyoshi.

After the Battle of Sekigahara, the entire province of Echizen was assigned by Tokugawa Ieyasu to his second son, Yūki Hideyasu in 1601 as Fukui Domain.

Throughout its history, Ōno suffered from severe financial problems; however, Doi Toshitada (1811–1869) implemented substantial reforms and introduced rangaku and western technology.

Following the Meiji restoration, the castle was pulled down, with the exception of a couple of gates which were given to nearby Buddhist temples, and the area was used for government buildings.