A prominent actor of classic films in the Turkish cinema, he has played a wide range of iconic characters in various genres, including drama, comedy.

[2] Şener Şen began acting in 1958 at the age of 17 as an amateur at the Yeşil Sahne Theater in Cağaloğlu.

He was the one of ensemble cast in classic comedy films Hababam Sınıfı, Tosun Paşa, Gülen Gözler, Süt Kardeşler, Şabanoğlu Şaban, Neşeli Günler, Bizim Aile.

[5] For his role as Nazım in Yavuz Turgul's movie Gönül Yarası (2005), he won the "Best Actor" award at the 42nd International Antalya Golden Orange Film Festival.

[6][7] On 28 December 2016, at the Presidential Culture and Arts Grand Prize ceremony, he received an award from President Recep Tayyip Erdoğan after which he said: "Stories tell us how we can live life.