Džaferović announced his candidacy in the Bosnian general election on 26 May 2018, running for Bosnia's three-person Presidency member, representing the Bosniaks.

[9] As the COVID-19 pandemic in Bosnia and Herzegovina started in March 2020, the Presidency announced Armed Forces' placement of quarantine tents at the country's borders intended for Bosnian citizens returning home.

[11] Three days later, on 5 March, Slovenian president Borut Pahor also came to Sarajevo and met with Džaferović, Komšić and Dodik, and stated that Slovenia will also donate 4,800 AstraZeneca COVID-19 vaccines for the pandemic.

[18] In August 2021, Džaferović and Komšić, without including Dodik, instructed the Ministry of Security to be available for putting out wildfires in Herzegovina which had formed a few days before.

Following Russia recognizing the Donetsk People's Republic and the Luhansk People's Republic as independent states on 21 February 2022, which are disputed territories in the Ukrainian region of Donbas, Džaferović condemned Russia’s moves to recognize the independence of Donetsk and Luhansk: "Bosnia and Herzegovina respects and supports the territorial integrity and sovereignty of Ukraine.

"[23]On 24 February 2022, Russian president Vladimir Putin ordered a large-scale invasion of Ukraine, marking a dramatic escalation of the Russo-Ukrainian War that began in 2014.

Regarding the invasion, Džaferović said that "Bosnia and Herzegovina stands with the people who suffered brutal attacks by Russian military forces in cities all over Ukraine.

"[24] In September 2020, Džaferović and his fellow Presidency members said that an EU candidate status for Bosnia and Herzegovina was possible in the year 2021 if the country "implements successful reforms".

[26] This was part of von der Leyen's visit to Bosnia and Herzegovina, since she some hours before opened the Svilaj border checkpoint and a bridge over the nearby Sava river, which bears the internationally important freeway Pan-European Corridor Vc.

[27] On 1 December 2021, Džaferović and Komšić met with German Minister of State for Europe Michael Roth, with the main topics of discussion being the political situation in Bosnia and Herzegovina, reform processes and activities on the country's EU path.

[28] On 20 May 2022, he met with European Council President Charles Michel, during his visit to Sarajevo, with whom he discussed about Bosnia and Herzegovina's accession to the EU.

[29] On 16 March 2021, Džaferović, Komšić and Dodik went on a state visit to Turkey to meet with Turkish President Recep Tayyip Erdoğan.

[31] Also on the meeting, Bosnia and Herzegovina and Turkey agreed on mutual recognition and exchange of driving licenses, as well as signing an agreement on cooperation in infrastructure and construction projects, which also refers to the construction of a highway from Bosnia's capital Sarajevo to Serbia's capital Belgrade; the agreement being signed by Minister of Communication and Traffic Vojin Mitrović.

[35] In April 2021, Džaferović sent a letter of concern to European Council President Charles Michel upon a supposed non-paper sent by Slovenian Prime Minister Janez Janša, regarding possible border changes in the Western Balkans.