The α- (alpha), β- (beta), and γ- (gamma) cyclodextrins correspond to six, seven, and eight glucose units, respectively.
The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic.
β-Cyclodextrin is moderately soluble in water and glycerin; well soluble in dimethyl sulfoxide, dimethylformamide, pyridine, HFIP, and ethylene glycol; and insoluble in ethanol and acetone.
[3] β-Cyclodextrin is widely used in medicine, pharmacy, food industry, textiles.
Hydrophobic forms of β- CD have been used as sustained release drug carriers.