β-Thromboglobulin (β-TG), or beta-thromboglobulin, is a chemokine protein secreted by platelets.
[3] Along with platelet factor 4 (PF4), β-TG is one of the best-characterized platelet-specific proteins.
[1][4] β-TG also has multiple biological activities, for instance being involved in maturation of megakaryocytes.
[5] β-TG also affects megakaryocyte maturation, and thus helps in regulating platelet production.
[9][10][11][12] Levels of β-TG have also been found to be increased or unchanged during normal pregnancy.