β-Zearalenol

β-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp.

[1] It is the β epimer of α-zearalenol and along with α-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism.

[2][3] A relatively high proportion of α-zearalenol is formed from zearalenone compared to β-zearalenol in humans.

[3] β-Zearalenol is about the same or slightly less potent as an estrogen relative to zearalenone.

[1]