Between 1928 and 1938, the Lezgin and Dargin alphabets had used Ꝗ, but since 1938, both corresponding languages are written with Cyrillic-based alphabets, using the digraph Кь in place of Ꝗ.
When used to write the Latin language, ꝗ could be used alone or as part of a word.
[1] Closely related is the letter Q with diagonal stroke (Ꝙ, ꝙ), which stood alone to abbreviate quod, qui and que in Latin.
[1] Ꝗ and Ꝙ, along with other letters of interest to scholars of medieval manuscripts, was added to the Unicode Standard in 2006 after a request by Michael Everson.
[1] It resides in the Latin Extended-D block of the Basic Multilingual Plane.