The .22 Nosler is designed to use the existing bolt face of an AR-15, and conversions to this caliber can be accomplished with a simple barrel swap.

The case diameter and taper resemble those of the 6.8mm Remington SPC, so Nosler recommends using a magazine designed for that cartridge.

[4][3][5] The name .26 Nosler refers to the first two digits in the caliber (0.264 in; 6.7 mm) of the bullets that the cartridge fires and the name of the company which created it.

The .26 Nosler is designed as a modern 6.5mm cartridge, using recent advances in firearm technology to attain exceptionally high muzzle velocities, up to 1,040 m/s (3,400 ft/s), and maintain an extremely flat trajectory.

The overall cartridge length of 84.8 mm (3.340 in) is the same as that of the .30-06 Springfield, allowing the use of widely available standard-length actions.

[8] When released, the .26 Nosler was claimed to be the most powerful commercial 6.5 mm cartridge in the world.

[9] The .26 Nosler, when loaded with 8.4 g (129 gr) AccuBond Long Range very-low-drag bullets, retains as much velocity at 370 m (400 yd) as the .260 Remington produces at the muzzle.

[14] This feature helps weight-conscious sportsmen to lighten their load before venturing into the backcountry.

The cases’ overall length also aids in quick follow-up shots, since the bolt throw is shorter than on a magnum action.

The dimension at that point on the .28 Nosler case is 0.051 mm (0.002 in) larger, and that reduces its body taper by just a tad.

Due to its greater length, the Remington case is about 25 percent more capacious than the Nosler.

[17] Since the .28 Nosler burns smaller powder charges than the 7mm RUM, barrel accuracy life is potentially a bit longer.

Introduced in 2016 (production release 2017), the .33 Nosler is a SAAMI approved and standardized cartridge.

The name .33 Nosler refers to the first two digits in the caliber (0.338 in; 8.6 mm) of the bullets that the cartridge fires and the name of the company which created it.

[16] The .33 Nosler is built on the same action length as the .338 Winchester Magnum but launches projectiles at a higher velocity.