GRS Domains supports the gTLDs founded and majority owned by venture capitalist Iain Roache.

GRS Domains operates the following sixteen gTLDs: Around 350,000 domains were originally registered under .science in 2016, but registrations dropped off sharply in 2017 and fell to around 14,000 in late 2019 as early registrations expired and were not renewed.

A study carried out in 2020 found that there had been little uptake of the .science domain by academics and researchers, the originally intended community.

Of the domains registered at this point, 39% did not return a website, 35% were parked for reselling, and another 10% were simply used as redirects.

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