It stars Glenn Close reprising her role as Cruella de Vil as she attempts to steal puppies for her "grandest" fur coat yet, with Ioan Gruffudd, Alice Evans, Tim McInnerny, Ian Richardson, Gérard Depardieu, Ben Crompton, Carol MacReady, Jim Carter, Ron Cook, David Horovitch, Timothy West, and the voice of Eric Idle in supporting roles.

Close and McInnerny were the only two actors from the 1996 film to return for the sequel, while Adrian Biddle and Anthony Powell reprised their respective duties as cinematographer and costume designer.

[2] A backstory film in its own continuity, Cruella, was released on May 28, 2021, with Emma Stone in the title role and Close acting as an executive producer.

[3] After four years in prison from the previous film, Cruella de Vil has been cured of her desire for fur coats by psychologist Dr. Pavlov.

She is released on probation but warned that if she breaks parole she will be immediately sent back to prison, as well as be forced to pay the remainder of her fortune, £8 million, to all the dog shelters in Westminster.

Cruella, therefore, mends her working relationship with her much-abused valet Alonzo and buys the Second Chance Dog shelter, owned by Kevin Shepherd, to save it from insolvency.

Dipstick's mate, Dottie, gives birth to three puppies: Domino, Little Dipper, and Oddball, who appears to be an albino, and begins to feel self-conscious about her lack of spots as she grows up.

After recognizing Dipstick and remembering her failed attempt of making a dalmatian fur coat, she enlists the help of French furrier Jean-Pierre LePelt.

Chloe and Kevin, exonerated from the theft accusation, return to London and are personally awarded the remnants of Cruella's fortune by Alonzo himself.

Production began in December 1998 and ended in mid-November 1999 without the use of John Hughes who wrote and produced the 1996 film, due to the critical failure of Flubber and the shutdown of Great Oaks Entertainment.

On November 7, Disney released the soundtrack to the movie, including pre-eminently, a cover of Paul Anka's "Puppy Love" (sung by Myra)[5][better source needed] and original songs: Mike Himelstein's "What Can a Bird Do?"

[15] A potential follow-up film to Cruella was discussed with Stone and Thompson mentioning the possibility of Close also appearing in a sequel with inspiration from The Godfather Part II.