104 Klymene is a large, dark Themistian asteroid that was discovered by J. C. Watson on September 13, 1868, and named after one of the many Clymenes in Greek mythology.

[6] It is orbiting the Sun with a period of 5.60 years and an eccentricity of 0.16.

It is classified as a C-type asteroid, indicating it probably has a carbonaceous composition.

The spectra indicates the presence of aqueous-altered minerals on the surface[7] based upon a sharp feature at a wavelength of 3 μm, and, as of 2015, is the only member of the Themis family found to show this absorption.

[9] It is listed as a member of the Hecuba group of asteroids that orbit near the 2:1 mean-motion resonance with Jupiter.