An earthquake occurred northeast of the city of Adana in the Armenian Kingdom of Cilicia (modern day Turkey) on 14 May 1269 at "the first hour of the night".

[2] Most sources give a death toll of 8,000 in the Armenian Kingdom of Cilicia in southern Asia Minor,[2] but a figure of 60,000 dead was reported by Robert Mallet in 1853 and repeated in many later catalogues.

At its southwestern end, the East Anatolian Fault (EAF) splits into two main branches, both of which link through to the Cyprus Arc.

[1] In the CFTI5MED Catalogue of strong earthquakes in Italy and in the Mediterranean area, the Istituto Nazionale di Geofisica e Vulcanologia (INGV) give a similar location for the epicenter but give a lower estimate for the magnitude of 6.4 Me  (a magnitude derived from seismic intensity, intended to be equivalent to Mw ).

[2] The monastery of Ark'akalin (thought to be located near Sis[8]) was severely damaged, leading to the deaths of priests and monks.