The epicenter was near Edo, the forerunner of present-day Tokyo, in the southern part of the Kantō region, Japan.

The earthquake triggered a major tsunami which caused many additional casualties, giving a total death toll of at least 5,233, possibly up to 200,000.

On both the Bōsō Peninsula and Miura Peninsula a clear paleo shoreline has been identified, indicating up to 5 metres (16 ft) of uplift near Mera (about 8 kilometres (5.0 mi) south of Tateyama) and up to 1.2 metres (3 ft 11 in) of uplift on Miura, increasing to the south.

[4] This distribution of uplift, coupled with modelling of the tsunami, indicate that at least two and probably three fault segments ruptured during the earthquake.

There was also a single death on the island of Hachijō-jima about 180 kilometres (110 mi) south of the earthquake's epicentre, where the tsunami was 3 metres (9.8 ft) high.