Enos Lowe[b] Democratic William E. Leffingwell[c] Democratic In the 1852 Iowa State Senate elections, Iowa voters elected state senators to serve in the fourth Iowa General Assembly.

To claim control of the chamber from Democrats, the Whigs needed to net 11 Senate seats.

Democrats maintained control of the Iowa State Senate following the 1852 general election with the balance of power shifting to Democrats holding 20 seats and Whigs having 11 seats (a net gain of 6 seats for both Democrats and Whigs).

[a] Democratic Senator William E. Leffingwell was chosen as the President of the Iowa Senate for the fourth General Assembly, succeeding Democratic Senator Enos Lowe in that leadership position.

[c][b] Source:[9] District boundaries were redrawn before the 1852 general election for the Iowa Senate: