The 1880 Troy Trojans improved slightly from the previous season, finishing with a 41–42 record and in 4th place in the National League.
Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.
= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games played; AB = At bats; H = Hits; Avg.
= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts