The 1880 premiership was won by the Geelong Football Club, which finished with a record of 9–1–2 in senior games and 14–2–2 overall.
Two sets of results are given: The clubs are listed in the order in which they were ranked in the Australasian newspaper.
The VFA had no formal process by which the clubs were ranked, so the below order should be considered indicative only, particularly since the fixturing of matches was not standardised; however, the top three placings were later acknowledged in publications including the Football Record and are considered official.
[2] Some scoring data is missing from the below table based on the availability of information.
J. Gibson (South Melbourne) served as captain of the Association team.