The 1887–88 Scottish Cup was the 15th season of Scotland's most prestigious football knockout competition.

Renton won the competition for the second time after they beat Cambuslang 6–1 in the final.

Glasgow University and Southern Athletic received a bye to the second round.

1 own goal Vale of Leven Wanderers received a bye to the third round.

Sources:[11] Abercorn, Albion Rovers, Arbroath, Cambuslang, Carfin Shamrock, Cowlairs, Dundee Our Boys, Queen's Park, St Bernard's and Thistle received a bye to the fifth round.