The 1898 Western Reserve football team represented Western Reserve University—known as Case Western Reserve University—in the American city of Cleveland, Ohio, during the 1898 college football season.

Led by David C. MacAndrew in his first season as head coach, Western Reserve compiled a record of 5–3 and outscored opponents by a total of 130 to 43.

Roland T. Meacham was the team captain.

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