The 1899 Louisville Colonels baseball team finished with a 75–77 record and ninth place in the National League.
Following the season, owner Barney Dreyfuss bought the Pittsburgh Pirates organization and folded his Louisville team.
Manager Fred Clarke and most of the players moved over to the Pirates where they enjoyed much more success in the coming years.
Louisville started the season with a 15–37 record after 52 games, but then went 60–40 in their last 100 in the first glimpse of what was to become a strong Pirates team in the years to come.
Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.