The empire wanted to prevent the formation of another semi-autonomous Armenian region in the eastern vilayets after its defeat in the First Zeitun Rebellion.
By this time, approaches to Sasun had been blocked by a division of the 4th Corps of the Ottoman army (eight battalions, later increased to fourteen).
Armenian forces consisted of 200 guerrillas under the command of Vahan, Hrayr and Andranik, along with Kevork Chavoush, Murad of Sebastia, Keri and others.
The first military action was undertaken by Kevork Chavush against local Kurds (Kor Slo) to prevent an attack on five Armenian villages in Kurdish-occupied territory.
By March 20, 1904, the Turks had finished preparations for addressing the uprising, and armies had plundered a number of boundary villages (which, by order from Hrayr, did not resist).
On April 12, Surb Arakelots monastery prior Arakel presented a decree from the Catholicos recommending that the Armenians surrender in exchange for amnesty.
Fierce hand-to-hand fighting began; from the eastern side of the village, Andranik and his troops struck in the Turkish rear.
On April 20, the Turks surrounded Gelieduzan with a mass artillery bombardment and fedayeen (led by Andranik) retreated to Talvorik by night.
The Turkish victory was accompanied by brutality: Women have been stolen, their breasts cut off, their stomachs ripped, children impaled, old men dismembered.
Young girls withdrew in uncountable set ... since May 5th, Turkish armies have wiped out one village after another in Berdakh, Mkragom, Alikrpo, Avazakhiubr and Arnist.
To hide traces of genocide from European observers, the Wāli of Bitlis gave orders to cut corpses into pieces and throw them into the Tigris.