The 1905–06 season was the 12th in the history of Southern League.
Fulham won Division One and Crystal Palace finished top of Division Two.
[1] No clubs applied to join the Football League.
A total of 18 teams contest the division, including 17 sides from previous season and one new team.
A total of 13 teams contest the division, including 9 sides from previous season and four new teams, all of them are newly elected teams.