The 1910 Lancashire Cup was the sixth year of the regional rugby league competition and once again a previous winner captured the trophy.
The cup was won by Oldham who beat Swinton in the final at Wheater's Field, Broughton, Salford, by a score of 4–3.
The attendance at the final was 14,000 and receipts £418.
For the fourth year in succession the same 12 clubs entered and four clubs awarded byes in the first round.
[1] Involved 4 matches (with four byes) and 12 clubs Scoring - Try = three (3) points - Goal = two (2) points - Drop goal = two (2) points