The 1910–11 season was the 17th in the history of Southern Football League.
Swindon Town won Division One for the first time and Reading finished top of the Division Two.
[1] Reading returned to Division One after previous season relegation along with Stoke.
No Southern League clubs applied for election to the Football League this season.
A total of twelve teams contest the division, including 7 sides from previous season Division Two A and Division Two B, two teams relegated from Division One and three new teams.