Led by tenth-year head coach Pop Warner, the Indians compiled a record of 11–1 and outscored opponents 298 to 49.

The season included one of the greatest upsets in college football history.

Against Harvard, Jim Thorpe scored all of the Indians' points in a shocking upset over the period powerhouse, 18–15.

One source claims Thorpe was "recognized as the greatest player of the year and a man whose kicking is likely to revolutionize the game.

"[2] College Football Hall of Fame members on the team include Thorpe, Gus Welch, and William "Lone Star" Dietz.