The A's finished first in the American League with a record of 101 wins and 50 losses, then went on to defeat the New York Giants in the 1911 World Series, four games to two, for their second straight World Championship.

Starting in 1911, the team was known for its "$100,000 infield", consisting of John "Stuffy" McInnis (first base), Eddie Collins (second base), Jack Barry (shortstop), and Frank "Home Run" Baker (third base) as well as pitchers Eddie Plank and Charles "Chief" Bender.

[1] Infielders Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.

= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games played; AB = At bats; H = Hits; Avg.

= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts AL Philadelphia Athletics (4) vs. NL New York Giants (2)