The Red Sox pitching was so strong in the 1915 series that the young Babe Ruth was not used on the mound and only made a single pinch-hitting appearance.

Arrangements for the Series were made on October 2, 1915, in a meeting of the team owners, league presidents and the National Commission at the Waldorf-Astoria Hotel in midtown Manhattan, New York City.

Rube Foster pitched a 3-hitter, allowing no walks, and retiring the last 10 Phillies he faced, and helped his own cause with the game-winning RBI single in the top of the ninth.

Ernie Shore held the Phillies scoreless until the eighth inning, winning 2–1, giving the Red Sox a 3–1 series lead.

The Red Sox won on three home runs by two of their outfielders, two cheapies by Harry Hooper (see above) and one by Duffy Lewis.

Fred Luderus homered for the Phillies only home run of the series in the bottom of the fourth inning.