The incumbent Democratic administration of Woodrow Wilson lost popularity after the conclusion of World War I in 1918, as American voters hoped to return to isolationism and avoid military conflict in the future.

Harding and the Republicans promised a new start for the nation and a disassociation from Europe's political troubles that most voters found appealing.

As a result, the Republicans picked up 63 seats in the House of Representatives, with most of the gains coming from Democratic-leaning districts in the big industrial cities and the border states.

Many of these districts elected Republican representatives for the only time in decades, and House Democratic leader Champ Clark was among those who lost reelection.

The 67th Congress is the most recent in which the Republican Party won greater than a two-thirds majority of seats in either chamber.