During the summer of 1921, a dispute between the Federazione Italiana Giuoco Calcio (FIGC) and the largest teams within the league arose.

This led to the creation of a new Italian football federation, the Confederazione Calcistica Italiana (CCI), who organised the 1921–22 Prima Divisione that ran concurrent to the FIGC championship.

The main tournament was completely divided in six independent sections, and each region had its own football champions that joined the national championship.

An agreement was found in late June: the Colombo Compromise by the boss of newspaper La Gazzetta dello Sport.

(*) Since the away goal rule wasn't applied, a tie-break was needed: Rivarolese and Pastore Turin were the sole two FIGC clubs which joined the regional champions and runners-up in the new First Division.