The Crimson finished with a 7–2–1 record under third-year head coach Bob Fisher.

[1][2] Walter Camp selected one Harvard player, guard John Fiske Brown, as a first-team member of his 1921 College Football All-America Team.

Charles Buell converted the extra point to make the score 7–0.

[4] Harvard's season-opening starting lineup was Kunhardt at center; Kane, Hubbard, Brocker, Brown, Lockwood, and Crocker also on the line; Buell at quarterback, Fitts and Owen at halfback, and Chapin at fullback.

[4] Harvard's starters for the game were Bradford at center, Hartley, Henry, Anthony, Grew, Hobson, and Macomber also on the line, Johnson at quarterback, Pfaffman and Rouillard at halfback, and Churchill at fullback.