In its eighth season under head coach William "Butch" Cowell,[b] the team compiled a 4–4–1 record, and outscored opponents by a total of 106 to 75.

The team played its home games in Durham, New Hampshire, at Memorial Field.

[4] In prior seasons, the school had operated as New Hampshire College of Agriculture and the Mechanic Arts.

[10] During the November 3 game against Lowell Textile, New Hampshire tackle Leonard P. Stearnes experienced abdominal pain.

[16] The 1925 edition of The Granite, New Hampshire's annual college yearbook, was dedicated to Stearnes.