Incumbent George E. Cryer was re-elected, defeating five challengers including judge Benjamin Franklin Bledsoe and Councilmember Miles S. Gregory and winning outright without the need of a general election.

[1] Municipal elections in California, including Mayor of Los Angeles, are officially nonpartisan; candidates' party affiliations do not appear on the ballot.

[6] In February 1925, Sylvester Weaver, president of the Los Angeles Chamber of Commerce, and Assemblymember Thomas L. Dodge withdrew from the race, leaving the main competition between Cryer and Bledsoe; Weaver endorsed Bledsoe for the race.

[7] Although Bledsoe was predicted to have an advantage due to a heavy vote, Cryer defeated all his opponents and was re-elected.

[1][8] The election was challenged by Edna Allen, who was an elector in the primary, who said that judges in all the districts counted ballots for Cryer that weren't meant for him.