The season was Harold Sebring's second and least successful campaign as the head coach of the Florida Gators football team.

[2] The highlights of the season were the Gators' two victories home field over the Florida Southern Moccasins and Clemson Tigers, which were interspersed among four close losses to the Chicago Maroons (6–12), the Ole Miss Rebels (7–12), the Mercer Bears (3–7) and the Kentucky Wildcats (13–18), crushing defeats by the Georgia Bulldogs (9–32) and coach Wallace Wade's undefeated Alabama Crimson Tide (0–49), and two low-scoring ties with the Hampden–Sydney Tigers (0–0) and the Washington & Lee Generals.

A 60-yard forward pass from Wally Marks to Laurie Apitz scored first for Chicago.

Florida took the lead after a Kentucky fumble on a punt was recovered by Tommy Owens.

[24] After a scoreless third period, Kentucky put together a winning touchdown drive in the fourth quarter.

[26] Wallace Wade's undefeated national champion Alabama Crimson Tide rolled over the Gators 49–0.

[30] Coach Pat Herron's Washington and Lee Generals tied Florida 7–7.

"The wolves began to clamor for Sebring's scalp as the 1926 season ended" wrote Pete Norton.

[31] The following chart provides a visual depiction of Florida's lineup during the 1926 season with games started at the position reflected in parentheses.