In their seventh season under head coach Harry Kipke, the Wolverines compiled a 4–4 record (2–3 against Big Ten Conference opponents, finished in a tie for seventh place in the Big Ten), and were outscored by opponents by a combined total of 131 to 68.

All eight opponents faced by the Wolverines during the 1935 season were led by head coaches who were later inducted into the College Football Hall of Fame.

Led by head coach Charlie Bachman and left halfback Kurt Warmbein, the Spartans again defeated the Wolverines, 25 to 6.

Lining up for a placekick, William Renner threw a short touchdown pass to Cedric Sweet.

[3] On October 26, 1935, Michigan played Lou Little's Columbia Lions at Baker Field in New York.

Michigan's final tally came on a five-yard touchdown pass from Bill Renner to Ernest Johnson, and Steve Remias kicked the extra point.

Al Barabas, star of the 1934 Rose Bowl, ran 74 yards for Columbia's only touchdown.

Penn had won its prior two games by a combined score of 101 to 0, and Michigan's victory was considered "an outstanding upset.

Bill Kurlish scored for Penn in the fourth quarter, and Johnny Viergever added a field goal for Michigan.

In a low-scoring match, Lowell Spurgeon kicked a 22-yard field goal for Illinois in the second quarter.

The Wolverines gained only 10 yards of total offense and secured only one first down, that one coming on an Illinois penalty for running into the punter in the third quarter.

It remains the worst defeat for a Michigan team in the history of the Michigan–Ohio State football rivalry.

[8] Ohio State finished the season tied with Minnesota for the Big Ten championship and ranked No.